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. 2022 Dec 5;12(12):2026. doi: 10.3390/life12122026

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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A simplified overview of non-histaminergic itch in PSO and AD. Abbreviations: AMP, antimicrobial peptides; DC, dendritic cell; FLG, filaggrin; IFN-γ, interferon-gamma; IL, interleukin; K, keratinocyte; OP, opioids; Mrgprx, Mas-related G-protein coupled receptor X; NK-1R, neurokinin 1 receptor; OPR, opioid receptor; OSMR, oncostatin M receptor; Th, T helper; TNF-α, tumor necrosis factor-alpha; TRPA1, transient receptor potential vanilloid 1; TRPV1, transient receptor potential ankyrin 1; TSLP, thymic stromal lymphopoietin.