Figure 1.

Blood glucose and weight change resulting from treatment. Baseline blood glucose and weight for each mouse were measured before treatment, and again after, preceding sacrifice. %Δ = ((post-treatment weight − initial weight) / initial weight) × 100. Symbols represent individual mice, with the mean shown as horizontal black bars. (A) Percent change in blood glucose over the period of treatment. (B) Percent change in weight that occurred in each treatment group. Asterisks indicate that changes were significantly different compared to control. Significance was determined by unpaired t-tests, ** indicates a p-value ≤ 0.01, and *** indicates p-value ≤ 0.001.