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. 2022 Nov 27;12(12):1184. doi: 10.3390/metabo12121184

Table 3.

Differential metabolites after fatal intoxication by OLA.

Compound Name Metabolite Identification p Trend VIP
Identified Levels Accurate Mass RT
Olanzapine 1 156.07026 6.742 1.38 × 10−9 up 1.874806
L-Acetylcarnitine 1 203.11574 9.1 9.85 × 10−8 down 1.763666
Propionylcarnitine 1 217.13124 9.878 3.44 × 10−7 down 1.717037
Creatine 2 131.06938 0.918 3.86 × 10−6 down 1.726218
L-Carnitine 2 161.10506 0.886 3.41 × 10−5 down 1.665984
Hexadecanedioic acid 2 286.21451 12.576 3.91 × 10−5 up 1.646536
L-Methionine 2 149.05097 0.983 3.91 × 10−5 down 1.678973
L-Tyrosine 2 181.07386 0.967 5.53 × 10−5 down 1.573716
3-Oxotetradecanoic acid 2 242.18822 12.827 6.44 × 10−5 up 1.608964
4-Hydroxycinnamic acid 2 164.0473 0.96 6.44 × 10−5 down 1.558905
2-Octanamidoacetic acid 2 201.13647 10.953 0.000151 up 1.54696
12-Hydroxystearic acid 2 300.26648 13.559 0.000372 up 1.455051
Indolelactic acid 2 205.07378 9.693 0.000372 up 1.489531
Taurine 2 125.01455 0.875 0.000501 down 1.508088
Vigabatrin 2 129.07892 0.757 0.001378 down 1.369638
L-Valine 2 117.07885 0.926 0.001598 down 1.440964
Allantoin 2 158.04388 0.921 0.002728 up 1.353355
Galactitol 2 182.07882 0.89 0.003248 up 1.230641
Gluconic acid 2 196.05826 0.888 0.006513 up 1.160182
Succinic acid 1 118.02652 0.902 0.006513 up 1.34286
Leucyl-Glutamate 2 260.13706 5.911 0.007345 down 1.281477
Threonic acid 2 136.03716 0.911 0.013767 up 1.080708
R-3-Hydroxydecanoic acid 2 188.14122 11.839 0.015148 down 1.103047
LysoPC2055Z,8Z,11Z,14Z,17Z/00 2 541.31669 12.317 0.016543 up 1.095663
Cholic acid 2 408.28784 11.728 0.017701 down 1.137465
Citric acid 2 192.02698 1.526 0.018878 up 1.072548
L-Lysine 2 146.10545 1.053 0.021913 down 1.01019
Hexanoylglycine 2 173.10519 9.126 0.026868 up 1.004025
Dodecanedioic acid 2 230.15171 10.764 0.038024 down 1.02619