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. 2022 Nov 24;10(12):2324. doi: 10.3390/microorganisms10122324

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Proposed catabolic pathway for poly(cis-1,4-isoprene). Poly(cis-1,4-isoprene) is cleaved to form oligo-isoprenoids with aldehyde and keto end groups (oligo-isoprene aldehydes). The tri- to penta-isoprene aldehydes are oxidized to oligo-isoprene acids by NF2_RS14000 and NF2_RS14385 in strain NBRC 15532.