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Effect of Bi. lactis MG741 on skin wrinkle formation such as (a) total wrinkle area, (b) mean length, (c) mean depth and (d) max wrinkle depth in UVB-exposed HR-1 mice. HR-1 mice were treated with Bi. lactis MG741 (1 × 109 CFU/head/day) orally and UVB irradiation on dorsal skin until 12 weeks. Data are indicated as means ± SE (n = 6). ** p < 0.01, and *** p < 0.001 vs. no-UVB control; # p < 0.05, ## p < 0.01, and ### p < 0.001 vs. UVB-exposed control.
