Table 1.
Calculation of C.I. in the combined treatment of CEN plus IR.
| Cristal Violet Assay | |||
| CEN (μg/mL) | IR (Gy) | Effect § | C.I. * |
| 100 | 2.5 | 0.476 | 0.44 |
| 200 | 5 | 0.565 | 0.60 |
| Clonogenic Assay | |||
| CEN (μg/mL) | IR (Gy) | Effect § | C.I. * |
| 100 | 2.5 | 0.66 | 0.29 |
| 200 | 5 | 0.70 | 0.40 |
| 100 | 5 | 0.61 | 0.82 |
| 200 | 10 | 0.77 | 0.48 |
| 200 | 5 | 0.70 | 0.43 |
§ Effects and fa values were obtained with the Crystal Violet assay or the clonogenic assay. * C.I. values were calculated using Compusyn software 1.0, as described in the Materials and Methods Section, at constant (radiation/CEN dose ratio 2.5/1 blue values) or not constant (red values) doses of radiation and CEN.