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. 2022 Dec 19;11(12):1556. doi: 10.3390/pathogens11121556

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Replication kinetics of the wild type (1st cell passage, white squares) and variants (10th cell passage, black squares) of field RABV isolates after 16, 24, 48, 72 and 96 h post-infection in a neuronal cell line. Viral loads obtained by qPCR from culture supernatants, shown as log10 genome copies/mL. (a) Great fruit-eating bat (Isolate 1069/18). (b) Dog (Isolate IP3629/11). (c) Mexican free-tailed bat (Isolate 203/21). (d) Great fruit-eating bat (Isolate 1833/21). (e) Great fruit-eating bat (Isolate 2193/21). (f) White-eared opossum (Isolate 2253/21). Data represent the mean ± SD of three independent experiments. ** (p < 0.01) and *** (p < 0.001) comparing the wild type and the respective variant.