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. 2022 Dec 2;8(6):2864–2873. doi: 10.3390/tomography8060240

Table 2.

Corneal Higher-Order Aberrations Parameters in Normal, Suspect Keratoconus, and Normal Groups.

Anterior HOAs
Indices Normal (n = 108) SKC (n = 42) KC (n = 70) p-Value p *
Mean SD Mean SD Mean SD Normal vs. SKC Normal vs. KC SKC vs. KC
Total HOAs 0.28 0.14 0.73 0.34 2.11 0.90 <0.0001 <0.0001 <0.0001 <0.0001
Trefoil Z (3, ±3) 0.12 0.07 0.30 0.23 0.56 0.27 <0.0001 <0.0001 <0.0001 <0.0001
Coma Z (3, ±1) 0.15 0.13 0.55 0.29 1.90 0.88 <0.0001 <0.0001 <0.0001 <0.0001
Spherical Z (4, 0) 0.02 0.15 −0.15 0.18 0.16 0.35 <0.0001 <0.0001 <0.0001 <0.0001
Posterior HOAs
Total HOAs 0.21 0.12 0.27 0.16 0.85 0.48 0.609 <0.0001 <0.0001 <0.0001
Trefoil Z (3, ±3) 0.13 0.10 0.18 0.14 0.60 0.38 0.82 <0.0001 <0.0001 <0.0001
Coma Z (3, ±1) 0.08 0.09 0.11 0.08 0.38 0.26 0.883 <0.0001 <0.0001 <0.0001
Spherical Z (4, 0) 0.04 0.06 −0.02 0.04 −0.08 0.11 <0.0001

n: number; SKC = suspect keratoconus; KC = Keratoconus; HOAs = higher-order aberrations; Z = Zernike; p: compares means between each two group. p *: compares the difference among the three groups; statistically significant values (p < 0.05). Values in bold are statistically significant.