Table 4.
EEG parameters in patients with Rett syndrome (RTT) and typically developed (TD) children. Following EEG parameters are presented: general slowing (GS), sensorimotor rhythm (SM), beta rhythm and EEG abnormalities. Max—maximal, Min—minimal, Fr—frequency, FrR—frequency rate as the ratio between high-frequency and low-frequency waves, Amp—amplitude, Index—the percentage of EEG parameters to the whole analyzed EEG fragments.
| RTT (n = 32) | TD (n = 41) | ||||
|---|---|---|---|---|---|
| Mean ± STD | Median | Mean ± STD | Median | Mann–Whitney U test | |
| GS_Fr | 2.55 ± 0.62 | 2.40 | 3.23 ± 0.65 | 3.2 | Z = −3.98, p = 0.0001 |
| Gs_Amp | 72.50 ± 38.33 | 70.00 | 35.24 ± 26.31 | 30 | Z = 4.20, p = 0.0001 |
| SM_Amp | 108.81 ± 49.62 | 107.50 | 73.17 ± 24.51 | 65 | Z = 3.346, p = 0.0007 |
| SM_MinFr | 3.16 ± 1.34 | 3.55 | 6.42 ± 1.39 | 6.3 | Z = −4.608, p < 0.0001 |
| SM_MaxFr | 9.89 ± 1.86 | 10.20 | 10.71 ± 1.19 | 10.91 | Z = −2.37, p = 0.017 |
| SM_Index | 18.95 ± 20.06 | 9.88 | 25.95 ± 14.48 | 23.4 | Z = −2.69, p = 0.007 |
| SM_FrR | 0.41 ± 0.14 | 0.40 | 0.66 ± 0.14 | 0.665 | Z = −5.54, p < 0.0001 |
| Beta_Amp | 20.13 ± 7.89 | 19.75 | 16.63 ± 4.74 | 15 | Z = 1.67, p = 0.084 |
| Epileptiform activity | 8.78 ± 13.53 | 5.13 | 0.86 ± 1.68 | 0.11 | Z = 5.63, p < 0.0001 |