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Pharmacokinetic parameters after the oral administration of NFT formulations.
| Tmax a (h) | Cmax b (ng/mL) | AUC0-8h b (ng·h/mL) | AUC0-∞ b (ng·h/mL) | t1/2 b (h) | |
|---|---|---|---|---|---|
| PM | 0.50 | 177 ± 75 | 438 ± 153 | 483 ± 142 | 2.6 ± 0.8 |
| PVPVA ASD | 0.50 | 130 ± 83 | 345 ± 176 | 664 ± 354 | 9.1 ± 10.0 |
| HPMAS ASD | 0.50 | 132 ± 49 | 475 ± 152 | 555 ± 200 | 2.7 ± 0.3 |
| Eudragit ASD | 1.0 | 232 ± 84 | 590 ± 163 | 685 ± 168 | 2.8 ± 0.8 |
a median, b mean ± SD.
