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. 2022 Dec 15;10(12):2152. doi: 10.3390/vaccines10122152

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Similar antigen-specific T cells responses observed after vaccination or infection. SARS-CoV-2 specific T cell responses after vaccination or natural infection analyzed by spectral flow cytometry (Figure S1). PBMCs isolated from convalescent (black, n = 7), J&J (blue, n = 8), Moderna (orange, n = 7), and Pfizer (green, n = 4) participants were analyzed for SARS-CoV-2 spike-specific CD4+ (A–C) and CD8+ (D–F) responses. Significance tested by Kruskal–Wallis test. y-axis indicates proportion of total CD4+ or CD8+ T cells that express the indicated activation markers or cytokines.