Table 2.
Antidepressant non-adherence prevalence (%) among the Castile and Leon (Spain) population.
| Non-Adherence Prevalence % (95% CI) | p | ||
|---|---|---|---|
| Sociodemographic Characteristics | |||
| Sex | |||
| Male | 20.56 (20.39–20.74) | 0.001 | |
| Female | 19.59 (19.42–19.76) | ||
| Urbanicity | |||
| Yes | 20.92 (20.75–21.1) | 0.001 | |
| No | 17.96 (17.79–18.12) | ||
| Institutionalized | |||
| Yes | 13.61 (13.47–13.76) | 0.001 | |
| No | 20.39 (20.22–20.57) | ||
| Health related characteristics | |||
| Multiple prescribers | |||
| Yes (≥3 prescribers) | 19.19 (19.02–19.36) | 0.001 | |
| No (<3 prescribers) | 20.8 (20.63–20.97) | ||
| Polypharmacy | |||
| Yes (≥5 drugs) | 18.43 (18.27–18.6) | 0.001 | |
| No (<5 drugs) | 24.85 (24.66–25.03) | ||
| Antidepressant class | |||
| TCAs | 23.99 (23.8–24.17) | 0.001 | |
| SSRIs | 20.19 (20.01–20.36) | ||
| Other antidepressants | 18.5 (18.34–18.67) | ||
| Mental health diagnostics | |||
| Pain (different etiologies) | 24.81 (24.62–24.99) | 0.001 | |
| Anxiety | 21.55 (21.37–21.72) | ||
| Depression and Anxiety | 19.47 (19.3–19.64) | ||
| Depression | 17.83 (17.67–17.99) | ||
| Other psychiatric diagnosis | 17.75 (17.59–17.92) | ||
Abbreviations: 95% CI: confidence interval, SSRIs, Selective Serotonin Reuptake Inhibitors, TCAs: Tricyclic Antidepressants.