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. Author manuscript; available in PMC: 2022 Dec 23.
Published in final edited form as: J Cell Physiol. 2019 Dec 25;235(6):5305–5317. doi: 10.1002/jcp.29416

Figure 3.

Figure 3.

NGF and TrkA expression was reduced in the discs of vegfr-1TK−/− mice compared to WT mice of the DDD groups. Representative immunofluorescence staining for NGF (A) and TrkA (D) in the IVD of DDD and sham mice at 12 weeks post-surgery (bars=200μm for the integral discs, bars=20μm for magnified NP and AF areas). Quantitative analyses showed that NGF (B, C) and TrkA (E, F) expression in IVDs of the DDD group of vegfr-1TK−/− mice was significantly lower than that in the IVDs of the DDD group of wt mice at 12 weeks after surgery. (n=5 per group) (***P< 0.001).