Figure 10.

NK-92 cytotoxicity in a co-culture model with HCT 116. NK-92 and HCT 116 were co-cultured at various target:effector cell ratios alone or in the presence of Ara-C/DS (10 nM Ara-C, 0.2 µg/mL DS). After 48 h, NK-92 cells were removed and the growth of HCT 116 was measured using the SRB assay (data represented as a triplicate ± SEM). Statistical analysis was performed using a 2-way ANOVA with Bonferroni post hoc test where **** p < 0.0001 and ** p < 0.01 compares Ara-C/DS treated cells to non-treated cells for the respective target:effector ratios; #### p < 0.0001, ### p < 0.001 and ## p < 0.01 compares the 1:5 and 1:10 target: effector ratios to the cultures devoid of NK-92 (1:0 ratio) for each respective treatment; and $$ p < 0.01 compares the 1:10 target: effector ratios to the 1:5 target: effector ratios for each respective treatment.