Table 2.
Assays | Sensitivity (95% CI) |
Specificity (95% CI) |
|||||
---|---|---|---|---|---|---|---|
1st week (6.1 d) N = 34 |
2nd week (11.2 d) N = 35 |
3rd week (17.8 d) N = 38 |
Overall N = 107 |
<2016 sera N = 52 |
Non-COVID-19 sera N = 58 |
Overall N = 110 |
|
Abbott IgG | 19 55.9% (46.5–65.3) |
30 85.7% (79.1–92.3) |
38 100% (99.3–100) |
87 81.3% (73.9–88.7) |
52 100% (99,3–100) |
57 98.3% (95.9–100) |
109 99.1% (97.3–100) |
FRENDTM IgG | 21 61.8% (52.6–71.0) |
33 94.3% (89.9–98.7) |
38 100% (99.3–100) |
92 85.9% (79.3–92.5) |
51 98.1% (95.5–100) |
57 98.3% (95.9–100) |
108 98.2% (95.7–100) |
Roche total antibodies | 17 50% (41.1–58.9) |
33 94.3% (90.2–98.5) |
37 97.4% (94.6–100) |
87 81.3% (73.9–88.7) |
51 98.1% (95.7–100) |
57 98.3% (95.9–100) |
108 98.2% (95.7–100) |
Snibe IgG | 17 50% (40.5–59.5) |
31 88.6% (82.6–94.6) |
37 97.4% (94.4–100) |
85 79.4% (71.7–87.1) |
48 92.3% (87.3–97.3) |
57 98.3% (95.9–100) |
105 95.5% (91.6–99.4) |
Beckman IgG | 18 52.9% (43.4–62.4) |
32 91.4% (86.1–96.7) |
37 97.4% (94.4–100) |
87 81.3% (73.9–88.7) |
52 100% (99.3–100) |
58 100% (99.3–100) |
110 100% (99.3–100) |
Mindray IgG | 20 58.8% (49.5–68.1) |
32 91.4% (86.1–96.7) |
38 100% (99.3–100) |
90 84.1% (77.2–91.0) |
52 100% (99.3–100) |
58 100% (99.3–100) |
110 100% (99.3–100) |
Mindray total antibodies | 24 70.6% (61.9–79.2) |
32 91.4% (86.1–96.7) |
38 100% (99.3–100) |
94 87.9% (81.7–94.1) |
52 100% (99.3–100) |
56 96.6% (93.2–99.9) |
108 98.2% (95.7–100) |
Siemens total antibodies | 16 47.1% (37.6–56.6) |
30 85.7% (79.1–92.3) |
37 97.4% (94.4–100) |
83 77.6% (69.7–85.5) |
51 98.1% (95.5–100) |
58 100% (99.3–100) |
109 99.1% (97.3–100) |
Vazyme sVNT | 25 73.5% (65.1–81.9) |
34 97.1% (93.9–100) |
38 100% (99.3–100) |
97 90.7% (85.2–96.2) |
51 98.1% (95.5–100) |
56 96.6% (93.2–99.9) |
107 97.3% (94.3–100) |
GenScript sVNT | 20 58.8% (49.5–68.1) |
33 94.3% (90.2–98.5) |
38 100% (99.3–100) |
91 85.0% (78.2–91.8) |
51 98.1% (95.5–100) |
58 100% (99.3–100) |
109 99.1% (97.3–100) |