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. 2022 Dec 23;8(12):e12614. doi: 10.1016/j.heliyon.2022.e12614

Table 2.

The sensitivity and specificity of each commercial immunoassay.

Assays Sensitivity (95% CI)
Specificity (95% CI)
1st week (6.1 d)
N = 34
2nd week (11.2 d)
N = 35
3rd week (17.8 d)
N = 38
Overall
N = 107
<2016 sera
N = 52
Non-COVID-19 sera
N = 58
Overall
N = 110
Abbott IgG 19
55.9% (46.5–65.3)
30
85.7% (79.1–92.3)
38
100% (99.3–100)
87
81.3% (73.9–88.7)
52
100% (99,3–100)
57
98.3% (95.9–100)
109
99.1% (97.3–100)
FRENDTM IgG 21
61.8% (52.6–71.0)
33
94.3% (89.9–98.7)
38
100% (99.3–100)
92
85.9% (79.3–92.5)
51
98.1% (95.5–100)
57
98.3% (95.9–100)
108
98.2% (95.7–100)
Roche total antibodies 17
50% (41.1–58.9)
33
94.3% (90.2–98.5)
37
97.4% (94.6–100)
87
81.3% (73.9–88.7)
51
98.1% (95.7–100)
57
98.3% (95.9–100)
108
98.2% (95.7–100)
Snibe IgG 17
50% (40.5–59.5)
31
88.6% (82.6–94.6)
37
97.4% (94.4–100)
85
79.4% (71.7–87.1)
48
92.3% (87.3–97.3)
57
98.3% (95.9–100)
105
95.5% (91.6–99.4)
Beckman IgG 18
52.9% (43.4–62.4)
32
91.4% (86.1–96.7)
37
97.4% (94.4–100)
87
81.3% (73.9–88.7)
52
100% (99.3–100)
58
100% (99.3–100)
110
100% (99.3–100)
Mindray IgG 20
58.8% (49.5–68.1)
32
91.4% (86.1–96.7)
38
100% (99.3–100)
90
84.1% (77.2–91.0)
52
100% (99.3–100)
58
100% (99.3–100)
110
100% (99.3–100)
Mindray total antibodies 24
70.6% (61.9–79.2)
32
91.4% (86.1–96.7)
38
100% (99.3–100)
94
87.9% (81.7–94.1)
52
100% (99.3–100)
56
96.6% (93.2–99.9)
108
98.2% (95.7–100)
Siemens total antibodies 16
47.1% (37.6–56.6)
30
85.7% (79.1–92.3)
37
97.4% (94.4–100)
83
77.6% (69.7–85.5)
51
98.1% (95.5–100)
58
100% (99.3–100)
109
99.1% (97.3–100)
Vazyme sVNT 25
73.5% (65.1–81.9)
34
97.1% (93.9–100)
38
100% (99.3–100)
97
90.7% (85.2–96.2)
51
98.1% (95.5–100)
56
96.6% (93.2–99.9)
107
97.3% (94.3–100)
GenScript sVNT 20
58.8% (49.5–68.1)
33
94.3% (90.2–98.5)
38
100% (99.3–100)
91
85.0% (78.2–91.8)
51
98.1% (95.5–100)
58
100% (99.3–100)
109
99.1% (97.3–100)