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. 2022 Dec 9;27(24):8712. doi: 10.3390/molecules27248712

Figure 13.

Figure 13

BMNs used in combination therapy. (a) Schematic diagram of the therapeutic function of HMOTP@Pt@Au@Dox. Reprinted with permission from Ref. [132]. Copyright © 2022 Elsevier B.V. (b) Schematic illustration of the key steps toward the synthesis of Au@Pt−DOX−PCM−PEG nanotherapeutic. Reprinted with permission from Ref. [133]. Copyright © 2022 American Chemical Society. (c) Schematic illustration of chemo-photothermal combinational therapy by the multifunctional Au@Pt NPs. Reprinted with permission from Ref. [134]. Copyright © 2017 American Chemical Society. (d) Time-resolved size change of the MDA−MB−231 tumors in nude mice after various treatments. Reprinted with permission from Ref. [133]. Copyright © 2022 American Chemical Society. (e) Relative tumor volume variation of the mice in different groups during treatment. Reprinted with permission from Ref. [134]. Copyright © 2017 American Chemical Society. * p < 0.05, ** p < 0.01.