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. 2022 Nov 23;15(12):1451. doi: 10.3390/ph15121451
PD-1 programmed cell death protein-1
PD-L1/2 programmed death-ligand 1/2
CTLA-4 cytotoxic T-lymphocyte-associated protein 4
TIM-3 T-cell immunoglobulin and mucin domain-3
LAG-3 lymphocyte activation gene-3
TIGIT T cell immunoreceptor with immunoglobulin and ITIM domains
PTMs Post-translational Modifications
GPI glycosylphosphatidylinositol
ER endoplasmic reticulum
OST oligosaccharyltransferase
ERAD ER-associated degradation
ERLAD ER-to-lysosomes-associated degradation
UDP-GlcNAc uridine diphosphate N-acetylglucosamine
HBP hexosamine biosynthetic pathway
OGT O-GlcNAc transferase
OGA O-GlcNAcase
TCR T-cell-receptor
MHC major histocompatibility complex
APCs antigen-presenting cells
FUT8 Fucosyltransferase 8
B3GNT3 β-1,3-N-acetylglucosaminyl-transferase
CSCs Cancer stem cells
EMT epithelial-mesenchymal transition
GSK3β glycogen synthase kinase 3β
TNBC Triple-Negative Breast Cancer
AMPK Adenosine 5′-monophosphate (AMP)-activated protein kinase
CTL cytotoxic T lymphocyte
IHC immunohistochemical
FFPE Formalin-fixed paraffin-embedding
PNGase F peptide-N-glycosidase F;
HNSCC head and neck squamous cell carcinoma
EGF/EGFR Epidermal Growth Factor/Epidermal Growth Factor Receptor
ICOS/ICOSL inducible co-stimulator/ inducible co-stimulator ligand
NK cells natural killer cells
NCRs natural cytotoxicity receptors
LSECtin liver sinusoidal endothelial cell lectin
TIGIT T cell immunoreceptor with immunoglobulin and ITIM domains
CRD cysteine-rich domains
Gal-9 galectin-9
Siglec Sialic acid-binding immunoglobulin-like lectin
IAP integrin-associated protein
SIRPα signal regulatory protein α
TAMs tumor-associated macrophages
NKG2D natural killer group 2D
MICA/B MHC class I polypeptide-related sequence A/B
SLAM Signaling Lymphocyte Activation Molecule
DC dendritic cells
SRPK2 serine/arginine-rich protein kinase 2
PGK1 phosphoglycerate kinase 1
TCA tricarboxylic acid
2F-Fuc 2-fluoro-L-Fucose
2-DG 2-deoxy-glucose
PARP Poly ADP-ribose polymerase
Fab fragment antigen binding
Fc fragment crystallizable
ADCC Antibody-dependent cell-mediated cytotoxicity