FIGURE 5.

Neuropsychiatric symptoms (NPS) associated multimodal brain regions and their predictivity in the cognitive progression. To summary the results here, the IPL, subcortical regions, HP, and frontal regions work together as the core structures to keep the neuropsychiatric symptoms and cognitive function. Correlation analysis and regression analysis indicate that these regions are significantly correlated with cognition. ALFF, amplitude of low frequency fluctuations; GMV, gray matter volume; HP, hippocampus; ITG, inferior temporal gyrus