Table 1.
Summary of Eligible Studies.
| Author | Country | Age at Intervention, Years | Intervention Group | Control Group | Duration of Intervention | Outcomes |
|---|---|---|---|---|---|---|
| Baumgartner [26], 2012 | South Africa | 6–11 | 50 mg*4/wk FeSO4 (n = 81) | Placebo (n = 80) | 8.5 months | KABC sequential processing: Triangles, Hand movement, Atlantis Delayed |
| Devaki [20], 2009 | India | 15–18 | 100 mg*6/wk EFe (n = 30) | Control placebo (n = 30) | 8 months | WAIS, Short term memory, long term memory, Scholastic performance test |
| Pollitt [27], 1989 | Thailand | 9–11 | FeSO4 50 mg/d for 2 weeks and FeSO4 100 mg/d for 14 weeks (n = 5) | Placebo (n = 4) | 4 months | IQ, Mathematics |
| Rezaeian [28], 2014 | Iran | 14–18 | 50 mg*2/wk FeSO4 (n = 100) | Control group (n = 100) | 16 weeks | Attention score |
| Seshadri (C) [29], 1989 | India | 8–15 | (1) 40 mg/d EFe (n = 16) (2) 30 mg/d EFe (n = 16) |
Placebo (n = 16) | 4 months | Mazes, Digit span, Visual recall |
| Seshadri (D) [29], 1989 | India | 8–15 | 60 mg/d EFe (n = 65) | Placebo (n = 65) | 8 months | Mazes, Digit span, Visual recall |
| Soemantri (A) [30], 1985 | Indonesia | Average 9.5 | (1) anemia: 10 mg/kg/d FeSO4 (n = 43) (2) Non-anemia: 10 mg/kg/d FeSO4 (n = 16) |
(1) anemia placebo (n = 35) (2) non-anemia placebo (n = 25) |
3 mouths | IQ |
| Soemantri (B) [31], 1989 | India | 8.1–11.6 | 2 mg/kg/d EFe (n = 37) | Placebo (n = 35) | 3 months | IQ, math scores |
| Sungthong [32], 2004 | Thailand | 6–13 | (1) 300 mg/d FeSO4 (n = 140); (2) 300 mg/wk. FeSO4 (n = 134) |
Placebo (n = 123) | 16 weeks | IQ, mathematics |
Abbreviations: EFe: elemental iron; FeSO4: ferrous sulfate; IQ: intelligence quotient; WAIS: Wechsler adult intelligence scale; KABC: Kaufman assessment battery for children; wk: week; d: day; mg: milligram; kg: kilogram.