Table 1.
Study design and schedule for the intervention.
| Intervention | Pre-Treatment | Day 0 | 6 W | 3 M | 4 M | 6 M | 12 M | 24 M |
|---|---|---|---|---|---|---|---|---|
| Verification of the selection criteria, and informed consent obtained | ✓ | |||||||
| Blood pressure and pulse rate measurement | ✓ | ✓ | ✓ | |||||
| Objective symptom, oral examination | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | |
| Blood test | ✓ | ✓ | ||||||
| Urinalysis | ✓ | |||||||
| Chest X-ray | ✓ | |||||||
| ECG | ✓ | |||||||
| Panoramic X-ray | ✓ | ✓ | ||||||
| CT | ✓ | |||||||
| Bone marrow aspiration, blood collection | ✓ | |||||||
| Cell transplantation | ||||||||
| Bone biopsy, implant installation |
W, weeks; M, months; CT, computed tomography; ECG, electrocardiogram.