Figure 7.
Chemical structures of key compounds. IC50 values show CTLA-4/B7-1 interaction inhibitory activity. Three amino acids (V10, H11, F12) on PGF00432 correspond to C4m-3127 H10V random loop: 1MHPFLPIVSVHF12.
Chemical structures of key compounds. IC50 values show CTLA-4/B7-1 interaction inhibitory activity. Three amino acids (V10, H11, F12) on PGF00432 correspond to C4m-3127 H10V random loop: 1MHPFLPIVSVHF12.