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. 2022 Dec 2;15(12):1506. doi: 10.3390/ph15121506

Figure 7.

Figure 7

Chemical structures of key compounds. IC50 values show CTLA-4/B7-1 interaction inhibitory activity. Three amino acids (V10, H11, F12) on PGF00432 correspond to C4m-3127 H10V random loop: 1MHPFLPIVSVHF12.