Table 2.

Clinicopathological characteristics of reported cases of MM with smooth muscle cell differentiation (Including Current Case)

Reference	Age/Sex	Sites	Cell morphology	Pigment	Melanocyctic markers	Other markers	Differentiation
Banerjee et al. 1996 [11]	54/F	The epigastric area and right axillary lymph node metastasis, the subcutaneous tissue of the left upper back, right inguinal nodes metastasis and metastasis around the iliac vessels	Plump spindle cells, polygonal cells and large numbers of multinucleated tumour giant cells	Absent	S100+, HMB-45-	a-SMA+, Desmin+, HHF-35+	Smooth muscle
Ul-Mulk et al. 2012 [12]	73/F	Right arm, right axillary nodes and multiple metastases to the liver, lung, breast and skin	Composed of two different contiguous morphological, respectively melanosomes and leiomyosarcoma	Present	S100+, Melan A+	a-SMA+, Desmin+	Smooth muscle
Morimoto et al. 2014 [13]	63/F	The left toe and left groin lymph node metastasis	The neoplasm was composed of pleomorphic spindle cells	Absent	S100+, MITF-1+, HMB-45+	a-SMA+, Desmin+	Smooth muscle
Prieto-Torres et al. 2017 [14]	69/F	The left scapular area	The tumor cells with rhabdoid and spindle morphology	Absent	S100+, SOX10+, Melan A-, HMB-45-	a-SMA+, Desmin+	Smooth muscle
Current case	54/M	The right nasal cavity	Epithelioid/rhabdoid and spindle cells	Present	S100+, SOX10+, Melan A+, HMB-45+, PNL2+	a-SMA+, Desmin+, Caldesmon+, Cloponin+	Smooth muscle