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. 2022 Dec 23;22:208. doi: 10.1186/s12873-022-00764-9

Table 1.

Characteristics of all 375 emergency department (ED) visits labelled by the endpoint adjudication committee

No sepsis (N = 300) Sepsis (N = 75)
Unique patients, count 271 71
Age [IQR] 60.0 [45.0, 69.0] 65.0 [56.0, 72.0]
Sex, male count (%) 159 (53.0%) 38 (50.7%)
Days symptoms prior ED visit, days [IQR] 3.0 [2.0, 5.0] 2.0 [1.0, 3.0]
Charlson Comorbidity Index 4.0 [2.0, 6.0] 5.0 [4.0, 7.0]
qSOFA
 0 235 (78.3%) 20 (26.7%)
 1 60 (20.0%) 32 (42.7%)
 2 5 (1.7%) 18 (24.0%)
 3 0 (0.0%) 5 (6.7%)
MEWS (IQR) 1.0 [0.0, 3.0] 5.0 [3.0, 6.5]
Immuno-compromised, count (%) 114 (38.1%) 21 (28.0%)
ED specialty,
 Haematology 52 (17.3%) 8 (10.7%)
 Internal Medicine 93 (31.0%) 33 (44.0%)
 Nephrology 58 (19.3%) 10 (13.3%)
 Oncology 54 (18.0%) 15 (20.0%)
 Other 43 (14.3%) 9 (12.0%)
Length of stay, days (IQR) 0.0 [0.0, 4.0] 7.0 [3.5, 12.5]
Primary infection noted in discharge letter, count (%)
 Cardiovascular 3 (0.7%) 4 (5.3%)
 Intra-abdominal 40 (13.3%) 6 (8.0%)
 No infection 26 (8.7%) 3 (4.0%)
 Other 21 (7.0%) 3 (4.0%)
 Respiratory tract infection 154 (51.3%) 37 (49.3%)
 Skin Infection 16 (5.3%) 4 (5.3%)
 Unknown 3 (1.0%) 0 (0.0%)
 Urinary tract infection 37 (12.3%) 18 (24.0%)
Broad spectrum antibiotics, count (%) 52 (17.3%) 51 (68.0%)
ICU admission*, count (%) 8 (2.7%) 10 (15.2%)
In-hospital mortality admission, count (%) 4 (1.3%) 11 (14.7%)

qSOFA was computed using the sepsis-3 criteria [22]. Both immunocompromised and broad-spectrum antibiotics definitions are in line with UMCU protocols and explained in Supplemental Table 3

ICU Intensive care unit

* Only patients that were applicable for ICU admission are shown