Table 2.
Characteristics of ESVEA definition, ESVEA prevalence, and outcomes.
| Study | Definition of ESVEA |
Detection of ESVEA | Prevalence of ESVEA n (%) |
Definition of Outcome |
Numbers of Outcome n (%) |
|---|---|---|---|---|---|
| Binici 2010 [12] |
≥30 SVEC/h or any episode of runs of ≥20 SVEC | 48 h ECG | 99 (14.6) | AF IS All-cause mortality |
22 (5.5) 27 (6.7) 87 (21.4) |
| Chong 2012 [13] |
>100 PACs/24 h | 24 h ECG | 107 (25) | AF IS Death |
60 (14) 41 (9.6) 60 (14) |
| Dewland 2013 [14] | The median PAC count was 2.5 beats/h (IQR, 0.8 to 9.5 beats/h) | 24 h ECG | - | AF All-cause mortality |
343 (27.2) 837 (66.4) |
| Yodogawa 2013 [33] | >100 PACs/24 h | 24 h ECG | - | AF | 17 (25) |
| Pinho 2015 [42] |
>30 APCs/h | 24 h ECG | 17 (9.2) | Recurrent IS/TIA | 22 (12) |
| Acharya 2015 [15] |
≥100 PACs/24 h | 24 h ECG | 486 (35.8) | AF | 155 (11.4) |
| Johnson 2015 [34] |
30 SVE/h and/or any SVT lasting for ≥20 consecutive beats | 24 h ECG | - | AF | 45 (11.7) |
| Lin 2015 [43] |
PAC burden >76 beats per day | 24 h ECG | 2072 (38.6) | All-cause mortality AF |
1209 (22.5) 418 (7.8) |
| Larsen 2015 [23] |
≥30 PACs/h or any episode of runs of ≥20 PACs | 48 h ECG | 99 (14.6) | IS All-cause mortality |
73 (10.8) 259 (38.2) |
| Vinther 2016 [22] |
≥3 PACs lasting less than 30 s during 48 h | 48 h of CICT | 161 (28) | Recurrent IS/TIA All-cause mortality AF |
73 (12.9) 158 (28) 22 (3.9) |
| Cabrera 2016 [44] |
Percentage of PAC (during the 24 h period) ≥0.2% | 24 h ECG | - | AF | 31 (10.4) |
| Marinheiro 2017 [35] |
>97 PACs/h | 24 h ECG | 124 (34.3) | IS All-cause mortality |
54 (14.9) 129 (35.6) |
| 30–97 PACs/h | 114 (31.5) | ||||
| Vinther 2017 [36] |
>14 PACs/h and ≥3 runs of PACs/24 h | 24 h ECG | 31 (12.1) | Recurrent stroke All-cause mortality |
20 (7.8) 34 (13.3) |
| Raman 2017 [37] |
PAC/h of sleep ≥ 21.15 | PSG based ECG | - | AF | 269 (11.4) |
| Persson 2019 [38] |
Top quartile of PACs (≥5.5 per hour) or SVT (≥0.13 per hour) | 24 h ECG | - | AF | 80 (21.2) |
| Ntaios 2020 [39] |
>0–1 SVE per 10 s | 12-lead ECG | 111 (13) | AF Recurrent IS All-cause mortality |
125 (14.7) 103 (12.1) 149 (17.5) |
| >1–2 SVE per 10 s | 57 (6.7) | ||||
| >2 SVE per 10 s | 58 (6.8) | ||||
| Sejr 2020 [40] |
0.5–1.5 PACs/h | 48 h ECG | 359 (24.7) | AF Recurrent IS Recurrent TIA All-cause mortality |
44 (2.9) 78 (5.4) 76 (5.2) 123 (8.5) |
| 1.6–5.9 PACs/h | 365 (25.1) | ||||
| ≥6.0 PACs/h | 362 (24.9) | ||||
| Hygrell 2021 [45] |
the top tenth percentile according to SVECs count | 30 s ECG | 709 (11.6) | AF IS Death |
387 (6.3) 161 (2.6) 354 (5.8) |
| Sasaki 2021 [46] |
PAC burden ≥ 0.4% | 24 h ECG | - | AF | 61 (29.3) |
| Vetta 2022 [41] |
PACs burden ≥ 7 | 24 h ECG | - | AF | 24 (21.4) |
SVEC—supraventricular ectopic complexes; AF—atrial fibrillation; ECG—electrocardiography; PACs—premature atrial complexes; IQR—interquartile range; APCs—atrial premature complexes; IS—ischemic stroke; TIA—transient ischemic attack; SVE—supraventricular extrasystoles; SVT—supraventricular tachycardias; CICT—continuous inpatient cardiac telemetry; SVECs—supraventricular ectopic complexes; PSG—polysomnogram.