Table 1.
Baseline characteristics of patients in the GMrepo database
| Variable | Before matching (n = 709) | After matching (n = 172) | ||||
|---|---|---|---|---|---|---|
| CRC (n = 318) | Control (n = 391) | p | CRC (n = 86) | Control (n = 86) | p | |
| Age (years, M, IQR)† | 63 (13) | 68 (12) | 0.037* | 64 (10) | 65 (10) | 0.985 |
| Age (n, %) | 0.015* | 0.542 | ||||
| < 65 years | 197 (39.1%) | 307 (60.9%) | 40 (47.6%) | 44 (52.4%) | ||
| ≥ 65 years | 101 (49.3%) | 104 (50.7%) | 46 (52.3%) | 42 (47.7%) | ||
| Sex (n, %) | 0.003* | 1.00 | ||||
| Male | 216 (49.2%) | 223 (50.8%) | 56 (50%) | 56 (50%) | ||
| Female | 102 (37.8%) | 168 (62.2%) | 30 (50%) | 30 (50%) | ||
| Country (n, %) | 0.015* | 1.00 | ||||
| Japan | 36 (47.4%) | 40 (47.4%) | 9 (50%) | 9 (50%) | ||
| China | 64 (54.2%) | 54 (45.8%) | 20 (50%) | 20 (50%) | ||
| United States | 24 (41.2%) | 33 (57.9%) | 3 (50%) | 3 (50%) | ||
| Italy | 22 (50%) | 22 (50%) | 6 (50%) | 6 (50%) | ||
| Germany | 79 (37.3%) | 133 (67.2%) | 16 (50%) | 16 (50%) | ||
| Austria | 73 (36.1%) | 129 (63.9%) | 32 (50%) | 32 (50%) | ||
| BMI (kg/m2, M, IQR)† | 25.2 (5.72) | 24.9 (6.14) | 0.748 | 25.00 (6.12) | 25.34 (5.86) | 0.834 |
| BMI (n, %) | 0.387 | 0.937 | ||||
| Normal | 148 (42.3%) | 202 (57.7%) | 34 (51.5%) | 32 (48.5%) | ||
| Overweight | 112 (44.1%) | 142 (55.9%) | 28 (48.3%) | 30 (51.7%) | ||
| Obesity | 38 (36.2%) | 67 (63.8%) | 24 (50%) | 24 (50%) | ||
CRC colorectal cancer, BMI body weight index
* p < 0.05
†p value was derived from the Mann‒Whitney test in data of continuous variables with abnormal distribution (M, Median; IQR, Interquartile Range). The p value was derived from the chi-square test or Fisher’s exact test in data of categorical variables from colorectal cancer and healthy controls (n, %)