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Pharmacokinetic parameters of 6-OH-CLX in the solvent control and SM groups after a single oral dose of 30 mg/kg CLX.
| PK Parameters | Control Group | Silymarin Group |
|---|---|---|
| AUC0-t (h × ng/mL) | 287.58 ± 106.13 | 155.36 ± 28.45 * |
| AUC0-∞ (h × ng/mL) | 325.78 ± 127.17 | 162.45 ± 22.18 * |
* p < 0.05 compared with the solvent control group.
