Table 1.
Summary of the GWAS data analysed with heritability estimates.
| Phenotype Class | Phenotype Name | Sample Size | Global h2SNP (observed scale) | Global h2SNP SE | Atlas or Source ID (Study and Year) | Ancestry |
|---|---|---|---|---|---|---|
| Cognitive traits | Cognitive performance | 257,828 | 0.20 | 0.01 | 4067 (Lee et al., 2018) |
European |
| Intelligence | 269,867 | 0.20 | 0.01 | 3785 (Savage et al., 2018) | ||
| Fluid intelligence (FI) score | 125,935 | 0.22 | 0.01 | 3413 (Watanabe et al., 2019) | ||
| FI test–FI3: word interpolation | 124,929 | 0.07 | 0.01 | 3402 (Watanabe et al., 2019) | ||
| FI test–FI6: conditional arithmetic | 96,994 | 0.05 | 0.01 | 3404 (Watanabe et al., 2019) | ||
| FI test–FI8: chained arithmetic | 68,065 | 0.07 | 0.01 | 3406 (Watanabe et al., 2019) | ||
| FI test–FI5: family relationship calculation | 99,934 | 0.03 | 0.01 | 3403 (Watanabe et al., 2019) | ||
| Educational attainment | 766,345 | 0.11 | 0.00 | 4066 (Lee et al., 2018) | ||
| Education–Qualifications | 318,526 | 0.11 | 0.00 | 3409 (Watanabe et al., 2019) | ||
| Age completed full-time education | 253,580 | 0.05 | 0.00 | 3203 (Watanabe et al., 2019) | ||
| Alzheimer’s disease (AD) | AD | 455,258 | 0.01 | 0.00 | (Jansen et al., 2019) | |
|
Gastrointestinal tract (GIT) disorders
|
Peptic ulcer disease (PUD) | 456,327 | 0.01 | 0.00 | (Wu et al., 2021) | |
| Gastroesophageal reflux disease (GERD) | 332,601 | 0.07 | 0.00 | (An et al., 2019) | ||
| Gastritis-duodenitis (GD) | 407,065 | 0.02 | 0.00 | Phecode 535 (Lee lab) | ||
| Diverticulosis | 362,094 | 0.04 | 0.00 | Phecode 562 (Lee lab) | ||
| Irritable bowel syndrome (IBS) | 455,321 | 0.01 | 0.00 | (Wu et al., 2021) | ||
| Inflammatory bowel disease (IBD) | 456,327 | 0.01 | 0.00 | (Wu et al., 2021) |
FI: fluid intelligence, SNP: single nucleotide polymorphism, SE: standard error, h2: heritability.