Table 3.
Num | Sex/Age | Symptom/Date of First Clinical Symptoms | mNGS/Date | G | GM | Infectionsites/Histology/Date | Antifungal | Surgery | Outcome at Day 90 |
---|---|---|---|---|---|---|---|---|---|
5 | F/42 | Fever, Coma/D-2 | Rhizopus oryzae/D-2 | N | N | Cerebral/-/- | L-AmB | No | Death/D4 |
6 | M/73 | Fever/D-3 | Rhizomucor pusillus/D4 | N | N | Pulmonary/-/- | L-AmB | No | Death/D30 |
7 | M/58 | Fever/D-19 | Rhizopus oryzae/D4 | N | N | Pulmonary/-/- | L-AmB, and posaconazole | No | Alive |
8 | F/14 | Fever, Swelling of right eye, Blurred vision, Headache/D-7 | Rhizopus oryzae/D2 | N | N | Rhino-cerebral/-/- | L-AmB/D2 | No | Death/D2 |
9 | M/40 | Headache/D-7 | Mucor/D3 | N | N | - | L-AmB, and posaconazole | Yes | Alive |
10 | M/38 | Fever/D-5 | Rhizopus oryzae/D7 | 118.86 | N | Pulmonary/-/- | L-AmB, and posaconazole | No | Death/D70 |
11 | M/64 | Fever/D-1 | Rhizomucor pusillus/D0 | N | N | Pulmonary/-/- | L-AmB, and posaconazole | No | Death/D12 |
12 | M/48 | Fever/D-2 | Rhizopus microspores/D1 | 267.57 | N | Pulmonary/-/- | - | No | Death/D2 |
13 | F/59 | Pectoralgia/D-3 | Rhizopus microspores/D2 | N | N | Pulmonary/-/- | L-AmB, and Posaconazole | No | Alive |
Abbreviations: G, 1,3 beta-Dglucan detection test; GM, galactomannan; L-AmB, liposomal amphotericin B; mNGS, Metagenomic next-generation sequencing; N, negative.