Table 7.
Results of statistical analysis of miRNA expression levels in blood plasma samples of apparently healthy women, patients with various histotypes of ovarian tumors and endometriosis.
| miRNA | Group | Control 1 (33–54 Age) * | Control 2 (25–33 Age) * | HGSOC, Cluster 1 * | HGSOC, Cluster 2 * | LGSOC * | SBT * | BSC * | Ovarian Endometrioma * | Deep Infiltrating Endometriosis * |
|---|---|---|---|---|---|---|---|---|---|---|
| miR-17-5p | Control 2 (25–33 age) | 0.1077 | NA | NA | NA | NA | NA | NA | NA | NA |
| miR-17-5p | HGSOC, cluster 1 | 0.017 | 0 | NA | NA | NA | NA | NA | NA | NA |
| miR-17-5p | HGSOC, cluster 2 | 0.2441 | 0.9699 | 0.0024 | NA | NA | NA | NA | NA | NA |
| miR-17-5p | LGSOC | 0.1306 | 0.935 | 0.0019 | 0.7925 | NA | NA | NA | NA | NA |
| miR-17-5p | SBT | 0.6787 | 0.0202 | 0.0224 | 0.0895 | 0.0987 | NA | NA | NA | NA |
| miR-17-5p | BSC | 0.7689 | 0.2174 | 0.0031 | 0.3355 | 0.5387 | 0.5732 | NA | NA | NA |
| miR-17-5p | Ovarian endometrioma | 0.649 | 0.1639 | 0.0108 | 0.3502 | 0.3494 | 0.412 | 0.9279 | NA | NA |
| miR-17-5p | Deep infiltrating endometriosis | 1 | 0.0594 | 0.0031 | 0.1246 | 0.2829 | 0.6615 | 0.8428 | 0.8328 | NA |
| miR-93-5p | Control 2 (25–33 age) | 0.0096 | NA | NA | NA | NA | NA | NA | NA | NA |
| miR-93-5p | HGSOC, cluster 1 | 0.0413 | 2.00 × 10−4 | NA | NA | NA | NA | NA | NA | NA |
| miR-93-5p | HGSOC, cluster 2 | 0.0125 | 0.9699 | 0.0062 | NA | NA | NA | NA | NA | NA |
| miR-93-5p | LGSOC | 0.0493 | 0.4952 | 0.0054 | 0.9578 | NA | NA | NA | NA | NA |
| miR-93-5p | SBT | 0.3732 | 0.093 | 0.0106 | 0.3432 | 0.7595 | NA | NA | NA | NA |
| miR-93-5p | BSC | 0.6495 | 0.1257 | 0.0667 | 0.2496 | 0.4176 | 0.8187 | NA | NA | NA |
| miR-93-5p | Ovarian endometrioma | 0.0073 | 0.9188 | 0.0016 | 0.6605 | 0.5116 | 0.2204 | 0.1896 | NA | NA |
| miR-93-5p | Deep infiltrating endometriosis | 0.0597 | 0.8667 | 0.0017 | 0.4371 | 0.8212 | 0.2665 | 0.2657 | 0.4865 | NA |
| miR-16-5p | Control 2 (25–33 age) | 0 | NA | NA | NA | NA | NA | NA | NA | NA |
| miR-16-5p | HGSOC, cluster 1 | 0.1184 | 0 | NA | NA | NA | NA | NA | NA | NA |
| miR-16-5p | HGSOC, cluster 2 | 0.2441 | 0.0016 | 0.0365 | NA | NA | NA | NA | NA | NA |
| miR-16-5p | LGSOC | 0.008 | 0.0192 | 0.0029 | 0.4923 | NA | NA | NA | NA | NA |
| miR-16-5p | SBT | 0.0073 | 0.001 | 0.0066 | 0.4537 | 0.9812 | NA | NA | NA | NA |
| miR-16-5p | BSC | 0.0457 | 0.0087 | 0.0063 | 0.3845 | 0.9742 | 0.7231 | NA | NA | NA |
| miR-16-5p | Ovarian endometrioma | 0.0821 | 6.00 × 10−4 | 0.0037 | 0.8836 | 0.1971 | 0.2962 | 0.4491 | NA | NA |
| miR-16-5p | Deep infiltrating endometriosis | 6.00 × 10−4 | 0.0414 | 5.00 × 10−4 | 0.0668 | 0.381 | 0.3048 | 0.5512 | 0.0688 | NA |
| miR-20a-5p | Control 2 (25–33 age) | 0.2005 | NA | NA | NA | NA | NA | NA | NA | NA |
| miR-20a-5p | HGSOC, cluster 1 | 0.0044 | 1.00 × 10−4 | NA | NA | NA | NA | NA | NA | NA |
| miR-20a-5p | HGSOC, cluster 2 | 0.21 | 0.791 | 0.0062 | NA | NA | NA | NA | NA | NA |
| miR-20a-5p | LGSOC | 0.1306 | 0.8065 | 1.00 × 10−4 | 0.9578 | NA | NA | NA | NA | NA |
| miR-20a-5p | SBT | 0.8902 | 0.1896 | 0.0027 | 0.2796 | 0.2449 | NA | NA | NA | NA |
| miR-20a-5p | BSC | 0.7689 | 0.1523 | 0.0119 | 0.2496 | 0.0804 | 0.8187 | NA | NA | NA |
| miR-20a-5p | Ovarian endometrioma | 0.8646 | 0.2171 | 0.0362 | 0.2561 | 0.1971 | 0.8079 | 0.8801 | NA | NA |
| miR-20a-5p | Deep infiltrating endometriosis | 0.4696 | 0.0529 | 0.0021 | 0.1025 | 0.1072 | 0.8841 | 0.8428 | 0.9759 | NA |
* The table shows the values of the statistical significance of the differences between the compared groups using the two-tailed Wilcoxon–Mann–Whitney test.