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. 2022 Dec 16;11(12):1551. doi: 10.3390/pathogens11121551

Table 1.

Characteristics of participants by age groups, no TB.

All (≥18 y/o) YA
(18–44 y/o)
MAA
(45–64 y/o)
ELD
(≥65 y/o)
YA vs. MAA vs. ELD
n = 913 n = 455 n = 333 n = 125 p Value
Sociodemographics
Male sex 294 (32.1%) 155 (33.8%) 106 (31.7%) 33 (26.4%) 0.263
Education, High school or higher 354 (38.6%) 242 (52.8%) 99 (29.6%) 13 (10.4%) <0.001
Current or past smoker 260 (28.4%) 131 (28.6%) 96 (28.7%) 33 (26.4%) 0.868
TB-related variables
Recent TB exposure 676 (73.7%) 363 (79.3%) 246 (73.7%) 67 (53.6%) <0.001
Past TB 23 (2.5%) 11 (2.4%) 8 (2.4%) 4 (3.2%) 0.872
Latent TB infection 507 (55.3%) 238 (52%) 191 (57.2%) 78 (62.4%) 0.093
BCG vaccination 821 (89.5%) 420 (91.7%) 290 (86.8%) 111 (88.8%) 0.136
Type 2 diabetes and other conditions
Type 2 diabetes 242 (26.4%) 60 (13.1%) 135 (40.4%) 47 (37.6%) <0.001
Overweight/obese, BMI ≥ 25 705 (76.9%) 354 (77.3%) 263 (78.7%) 88 (70.4%) 0.184
Central obesity (M ≥ 0.90 M; F ≥ 0.86) 712 (77.6%) 328 (71.6%) 282 (84.4%) 102 (81.6%) <0.001
High cholesterol (200 mg/dL) 153 (16.7%) 42 (9.2%) 85 (25.5%) 26 (20.8%) <0.001
High LDL (100 mg/dL) 388 (42.3%) 147 (32.1%) 180 (53.9%) 61 (48.8%) <0.001
Low HDL (40 M, 50 F, mg/dL) 655 (71.4%) 349 (76.2%) 221 (66.2%) 85 (68.0%) 0.006
High Triglycerides (150 mg/dL) 268 (29.2%) 113 (24.7%) 117 (35.0%) 38 (30.4%) 0.006
Macrovascular diseases 234 (25.5%) 41 (9.0%) 114 (34.1%) 79 (63.2%) <0.001
Microvascular diseases 212 (23.1%) 58 (12.7%) 98 (29.3%) 56 (44.8%) <0.001
Anti-inflammatory medications 171 (18.7%) 66 (14.4%) 65 (19.5%) 40 (32%) <0.001

p values calculated by chi-square or Fisher’s exact. When comparison of the three age groups had p values ≤ 0.099, further comparisons were made for ELD vs. YA or MAA. Significant/borderline significant difference between YA or MAA vs. ELD are indicated by bold format of the percentages; p ≤ 0.099 shown in bold; Normal range values shown in parenthesis; M, males; F, females; N/A, not applicable.