Table 3.
Proteins differentially regulated (0.8 ≥ FC ≥ 1.2) in CSf- or BC-treated vs. pCTRL synoviocytes identified by high-resolution LC-MS/MS.
| Accession | Gene Name | Description | CSf vs. pCTRL | BC vs. pCTRL |
|---|---|---|---|---|
| Q96HE7 | ERO1A | ERO1-like protein alpha | 1.2 | 1.1 |
| Q12929 | EPS8 | Epidermal growth factor receptor kinase substrate 8 | 1.3 | 1.1 |
| Q99714 | HSD17B10 | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.2 | 1.1 |
| O00442 | RTCA | RNA 3′-terminal phosphate cyclase | 1.3 | 1.1 |
| Q9H3P7 | ACBD3 | Golgi resident protein GCP60 | 1.4 | 1.1 |
| P55010 | EIF5 | Eukaryotic translation initiation factor 5 | 1.2 | 1.1 |
| Q14258 | TRIM25 | E3 ubiquitin/ISG15 ligase TRIM25 | 1.3 | 1.1 |
| Q00059 | TFAM | Transcription factor A, mitochondrial | 1.2 | 1.1 |
| P67809 | YBX1 | Y-box-binding protein 1 | 1.2 | 1.1 |
| Q9HCC0 | MCCC2 | Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial | 1.2 | 1.1 |
| Q01433 | AMPD2 | AMP deaminase 2 | 1.2 | 1.1 |
| O00534 | VWA5A | von Willebrand factor A domain-containing protein 5A | 1.3 | 1.1 |
| P33527 | ABCC1 | Multidrug resistance-associated protein 1 | 1.2 | 1.1 |
| P17096 | HMGA1 | High mobility group protein HMG-I/HMG-Y | 0.8 | 1.1 |
| P42345 | MTOR | Serine/threonine-protein kinase mTOR | 1.2 | 1.1 |
| P16435 | POR | NADPH--cytochrome P450 reductase | 1.3 | 1.1 |
| Q7Z4H8 | POGLUT3 | Protein O-glucosyltransferase 3 | 1.2 | 1.1 |
| P62805 | H4 | Histone H4 | 1.3 | 1.1 |
| P53999 | SUB1 | Activated RNA polymerase II transcriptional coactivator p15 | 1.2 | 1.0 |
| P17612 | PRKACA | cAMP-dependent protein kinase catalytic subunit alpha | 1.2 | 1.0 |
| Q9UJY1 | HSPB8 | Heat shock protein beta-8 | 1.2 | 1.0 |
| P20962 | PTMS | Parathymosin | 0.8 | 1.0 |
| Q9Y5M8 | SRPRB | Signal recognition particle receptor subunit beta | 1.2 | 1.0 |
| P05186 | ALPL | Alkaline phosphatase, tissue-nonspecific isozyme | 1.2 | 1.0 |
| Q07020 | RPL18 | 60S ribosomal protein L18 | 1.2 | 1.0 |
| P42677 | RPS27 | 40S ribosomal protein S27 | 1.2 | 1.0 |
| Q687X5 | STEAP4 | Metalloreductase STEAP4 | 1.2 | 1.0 |
| Q8N257 | H2BU1 | Histone H2B type 3-B | 1.2 | 1.0 |
| Q86VB7 | CD163 | Scavenger receptor cysteine-rich type 1 protein M130 | 0.7 | 1.0 |
| Q9NVJ2 | ARL8B | ADP-ribosylation factor-like protein 8B | 1.2 | 1.0 |
| P16930 | FAH | Fumarylacetoacetase | 1.2 | 1.0 |
| P08648 | ITGA5 | Integrin alpha-5 | 0.7 | 1.0 |
| P16070 | CD44 | CD44 antigen | 0.8 | 1.0 |
| P52566 | ARHGDIB | Rho GDP-dissociation inhibitor 2 | 0.8 | 0.9 |
| P41240 | CSK | Tyrosine-protein kinase CSK | 0.8 | 0.9 |
| Q9HC35 | EML4 | Echinoderm microtubule-associated protein-like 4 | 0.8 | 0.9 |
| Q96DR8 | MUCL1 | Mucin-like protein 1 | 1.0 | 6.7 |
| Q9GZT8 | NIF3L1 | NIF3-like protein 1 | 1.1 | 1.8 |
| Q9NZT1 | CALML5 | Calmodulin-like protein 5 | 1.1 | 1.7 |
| Q9NQC3 | RTN4 | Reticulon-4 | 1.1 | 1.6 |
| P84101 | SERF2 | Small EDRK-rich factor 2 | 1.0 | 1.3 |
| P02795 | MT2A | Metallothionein-2 | 1.0 | 1.3 |
| P17936 | IGFBP3 | Insulin-like growth factor-binding protein 3 | 1.1 | 1.3 |
| P50552 | VASP | Vasodilator-stimulated phosphoprotein | 1.0 | 1.3 |
| Q9UMS6 | SYNPO2 | Synaptopodin-2 | 1.1 | 1.3 |
| Q5SW79 | CEP170 | Centrosomal protein of 170 kDa | 1.1 | 1.3 |
| Q13459 | MYO9B | Unconventional myosin-IXb | 1.1 | 1.2 |
| Q9UNE7 | STUB1 | E3 ubiquitin-protein ligase CHIP | 1.1 | 1.2 |
| P25685 | DNAJB1 | DnaJ homolog subfamily B member 1 | 0.9 | 1.2 |
| Q9Y2H0 | DLGAP4 | Disks large-associated protein 4 | 1.0 | 1.2 |
| Q01469 | FABP5 | Fatty acid-binding protein 5 | 0.9 | 1.2 |
| Q562R1 | ACTBL2 | Beta-actin-like protein 2 | 0.9 | 0.8 |