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. 2022 Nov 23;12(12):1946. doi: 10.3390/jpm12121946

Table 1.

Represents the GARS SNPs and VNTRs (snapshot).

Gene Polymorphism Location Risk Allele(s)
DRD1 rs4532 Chr 5 A
DRD2 rs1800497 Chr 11 A
DRD3 rs6280 Chr 3 C
DRD4 rs1800955 Chr 11 C
48 bases Repeat Chr 11, Exon 3 7R, 8R, 9R, 10R, 11R
COMT rs4680 Chr 22 G
OPRM1 rs1799971 Chr 6 G
DAT1 40 bases Repeat Chr 5, Exon 15 3R, 4R, 5R, 6R, 7R, 8R
MAOA 30 bases Repeat Chr X, Promoter 3.5R, 4R
Serotonin Transporter SLC6A4 (5-HTTLPR) 43 bases Repeat plus rs25531 Chr 17 LG, S
GABA(A) Receptor, Alpha-3 GABRB3 CA-Repeat DNR Chr 15 (downstream) 181

Abbreviations: Dopamine receptor D1 (DRD1), dopamine receptor D2 (DRD2), dopamine receptor D3 (DRD3), dopamine receptor D4 (DRD4), catecholamine-methyltransferase (COMT), opioid receptor mu 1 (OPRM1), dopamine transporter (DAT1), monoamine oxidase A (MAOA), serotonin-transporter-linked promoter region (5HTTLPR), Gamma-aminobutyric acid type A receptor subunit beta3 (GABRB3).