Table 1.
Gene | Polymorphism | Location | Risk Allele(s) |
---|---|---|---|
DRD1 | rs4532 | Chr 5 | A |
DRD2 | rs1800497 | Chr 11 | A |
DRD3 | rs6280 | Chr 3 | C |
DRD4 | rs1800955 | Chr 11 | C |
48 bases Repeat | Chr 11, Exon 3 | 7R, 8R, 9R, 10R, 11R | |
COMT | rs4680 | Chr 22 | G |
OPRM1 | rs1799971 | Chr 6 | G |
DAT1 | 40 bases Repeat | Chr 5, Exon 15 | 3R, 4R, 5R, 6R, 7R, 8R |
MAOA | 30 bases Repeat | Chr X, Promoter | 3.5R, 4R |
Serotonin Transporter SLC6A4 (5-HTTLPR) | 43 bases Repeat plus rs25531 | Chr 17 | LG, S |
GABA(A) Receptor, Alpha-3 GABRB3 | CA-Repeat DNR | Chr 15 (downstream) | 181 |
Abbreviations: Dopamine receptor D1 (DRD1), dopamine receptor D2 (DRD2), dopamine receptor D3 (DRD3), dopamine receptor D4 (DRD4), catecholamine-methyltransferase (COMT), opioid receptor mu 1 (OPRM1), dopamine transporter (DAT1), monoamine oxidase A (MAOA), serotonin-transporter-linked promoter region (5HTTLPR), Gamma-aminobutyric acid type A receptor subunit beta3 (GABRB3).