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. 2022 Nov 22;14(12):2591. doi: 10.3390/v14122591

Figure 4.

Figure 4

Sequences of wild-type and insert-containing human immunodeficiency virus type 2 (HIV-2) integrase (from codon 226 to 240). Alignment of amino acids sequence of the reference strain and sequences of integrase found in patients after initiating the RAL-based regimen. Insertions described by Le Hingrat and colleagues lead to a high level of RAL and EVG resistance and a moderate resistance to DTG and CAB [69].