Table 2.

Experimental variables and results in the Box–Behnken design (n = 3).

Std Order		Factors		Particle Size (nm)
	pH	Amount of Ch (mg)	Reaction Temperature (°C)
1	8	4	55	148 ± 6
2	12	4	55	111 ± 7
3	8	20	55	261 ± 9
4	12	20	55	199 ± 6
5	8	12	25	181 ± 3
6	12	12	25	150 ± 22
7	8	12	85	183 ± 2
8	12	12	85	153 ± 18
9	10	4	25	117 ± 6
10	10	20	25	210 ± 25
11	10	4	85	105 ± 9
12	10	20	85	195 ± 10
13	10	12	55	154 ± 25
14	10	12	55	156 ± 33
15	10	12	55	159 ± 26