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Model of the mediation of the observed relationship between TMAO and PCSK9 by IL-8. Model adjusted for BMI and ASCVD risk score, (n = 60). ASCVD: atherosclerotic cardiovascular disease; BMI: body mass index; IL: interleukin; TMAO: trimethylamine N-oxide; PCSK9: proprotein convertase subtilisin/kexin type 9. Created with BioRender.com (accessed on 25 February 2022).
