Table 1.
Sr. No. | Formulation | Loaded Drug Contents at pH 6.8 (mg) | |
---|---|---|---|
1. | Carbopol-co-poly AMPS hydrogels | 974.2 ± 1.25 | |
2. | Carbopol-co-poly MAA hydrogels | 1077.9 ± 1.10 | |
3. | Carbopol-co-poly ITA-MAA hydrogels | 872.42 ± 1.08 | |
Sr. No. | Formulation | Increase in Weight (g) | % Absorbency |
1. | Carbopol-co-poly AMPS hydrogels | 0.663 − 0.264 = 0.399 | 83 |
2. | Carbopol-co-poly MAA hydrogels | 0.229 − 0.196 = 0.03 | 16.8 |
3. | Carbopol-co-poly ITA-MAA hydrogels | 0.558 − 0.439 = 0.12 | 27.10 |
Sr. No. | Formulation | Sol Fraction (%) | Gel Fraction (%) |
1. | Carbopol-co-poly AMPS hydrogels | 9.46 ± 1.01 | 90.54 ± 1.01 |
2. | Carbopol-co-poly MAA hydrogels | 8.35 ± 1.32 | 91.65 ± 1.32 |
3. | Carbopol-co-poly ITA-MAA hydrogels | 9.04 ± 1.08 | 90.96 ± 1.08 |
Values are expressed as Mean ± SD, n = 3.