Figure 2.
Peripheral neuropathic pain targets (non-opioid). Nav—voltage gated sodium channels, TRPV1—transient receptor potential vanilloid 1 channel, TRPA—transient receptor potential ankyrin channel, TRPM8—transient receptor potential melastatin 8 channels, VGCC—voltage-gated calcium channels, NMDAR—N-methyl-D-aspartic acid receptor, COX-2—cyclooxygenase 2, GABAR—GABA receptor, SNAP-23 and SNAP-25—SNARE protein complex components.