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. 2022 Dec 9;14(24):5253. doi: 10.3390/nu14245253

Table 1.

Characteristics of the included studies (alphabetically by author).

Authors Study Design Sample Size, Sample (Population) Setting (Context) Country Collection Period Phenomenon of Interest Sustainability Factors Quality
Alencar and Seidl (2010) [26] Cross-sectional 36 human milk donors Two human milk banks of the public health system of the Federal District Brazil May 2005–November 2006 The categories for the reasons (factors)of influencing the frequency of expressing and milk production were the ingestion of liquids, diet, routines of the mother going out, contraceptive use and return to work, baby feeding frequency, the presence of negative emotions, availability of time, frequency of expressing, growth of the baby, period of the day, physical fatigue and laziness, and nothing interfering with production. Donors’ frequency of milk extraction and milk production Weak *
Bocci et al. (2019) [27] Cross-sectional 304
human milk donors
A human milk bank in the province of Siena Italy January 2010–August 2017 Factors related to the volume of milk donated: length of donation period and gestational age (preterm delivery). Volume of milk donated Good *
Jarmoc et al. (2021) [28] Cohort study 3764 human milk donors (with a total of 10,525 donations) Mothers’ Milk Bank Northeast (MMBNE), a non-for-profit milk bank located in Newton Upper Falls, Massachusetts USA 1 January 2011–1 September 2019 Factor related to the volume of milk donated: whether the mother had a preterm or a term infant. Volume of milk donated Good *
Machado et al. (2015) [29] Qualitative 7 human milk donors A human milk bank located in the Virgen de las Nieves hospital, Granada Spain May–June 2013 Factors that influence women to continue donating their milk: milk bank support and family support of donation.Obstacles for women to remain donors: distance to the milk bank, support at work, and reduction in milk by the process of breastfeeding itself. Facilitators and barriers to donation continuation Good **
Mondkar et al. (2018) [30] Qualitative 56 service recipients, including human milk donors and key influencers, as well as 9 service providers Two health facilities under the Mumbai Municipal Corporation were purposively selected as case studies: a Level III facility with a human milk bank and a Level II facility without one. India August–November 2016 service providers reported a factor that could be a barrier to sustaining an adequate supply of DHM: staff shortage. Volume of milk donated Good **
Nangia et al. (2020) [31] Cross-sectional 1553 human milk donors The human milk bank of a tertiary care centre in a low- and middle-income country India 7 June 2017–28 February 2019 The volume of the donor milk collected is influenced by the service in which the baby is hospitalized (neonatal intensive care unit versus postnatal care ward). Volume of milk donated Moderate *
Osbaldiston & Mingle (2007) [32] Cross-sectional 87 human milk donors and 19 non donors (women who had pumped milk while breastfeeding their infants). Mothers’ milk bank at Austin (Texas) USA Fall 2005–spring 2006 Factors of interest apparently related to the amount of milk donated: thrush (in the infant); motive for donating milk (e.g., ’had too much milk and wanted to donate it’, as well as ‘needed to pump milk to stimulate lactation’); mother’s age. Volume of milk donated Moderate *
Pimenteira Thomaz et al. (2008) [33] Cross-sectional 737 human milk donors All three human milk banks in the State of Alagoas (located in the following hospitals: Maternity School Hospital Santa Mônica; Federal University of Alagoas School Hospital; Santa Casa de Misericórdia of São Miguel dos Campos). Brazil March 2004–February 2005 The most common characteristics of a regular donor in comparison with a first-time donor are having between four and seven pregnancies and possessing a higher education level. Donation recurrence (first-time versus regular donors) Moderate *
Quitadamo et al. (2018) [34] Cross-sectional 90 women, enrolled for donation The human milk bank of the Casa Sollievo della Sofferenza hospital, which is integrated into the Neonatology Service of the same hospital. Italy 1 January 2014–31 December 2015 Factors related to the volume of milk donated: maternal age; birth weight of the neonate; duration of donation; profession of the donor. Volume of milk donated Weak *
Sierra-Colomina et al. (2014) [35] Cross-sectional 391 human milk donors (for a total of 415 donations) The human milk bank of the Hospital Doce de Octubre, in the Madrid community, Spanish central region. Spain 1 January 2009–31 April 2013 Donors’ social and demographic variables related to the volume of donor milk delivered: previous donors; smaller gestational age of children; started donation at earlier stages of lactation. Volume of milk donated Good *

*: Quality appraisal of cross-sectional and cohort studies performed with the National Heart, Lung, and Blood Institute checklist. **: Quality appraisal of qualitative studies performed with the CASP qualitative checklist.