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. 2022 Dec 9;14(24):5253. doi: 10.3390/nu14245253

Table 3.

Summary of qualitative findings (factors influencing sustainability of DHM donation to HMB) and CERQual assessment.

17 Factors Summary of Review Finding Sustainability Factors Reported Impact on Donation Sustainability:
Increases +
Decreases −
Studies Contributing to the Review Study Design CERQual Assessment of Confidence in the Evidence * Explanation of CERQual Assessment
FACTORS RELATED TO DONORS’ INFANTS’ FEATURES
#14 Baby feeding frequency The frequency of the baby’s feeding was self-reported by some donors as potentially having a positive or negative influence on the frequency of milk extraction and milk production. Frequency of milk Extraction and milk production +/− Alencar and Seidl, 2010 [26] Quantitative Very low confidence ⊕○○○ One study with no or very minor concerns about coherence, moderate concerns regarding relevance, and serious concerns regarding adequacy and methodological limitations.
#15 Growth of the baby The baby’s growth was self-reported by some donors as potentially having a negative influence on the frequency of milk extraction and production. Frequency of milk extraction and milk production Alencar and Seidl, 2010 [26] Quantitative Very low confidence ⊕○○○ One study with no or very minor concerns about coherence, moderate concerns regarding relevance, and serious concerns about methodological limitations and adequacy.
FACTORS RELATED TO DONORS’ FEATURES: Health
#16 Self-hydration Self-hydration was self-reported by donors as potentially having a negative and/or positive influence on the frequency of milk extraction and milk production. Frequency of milk extraction and milk production +/− Alencar and Seidl, 2010 [26] Quantitative Very low confidence⊕○○○ One study with serious concerns about methodological limitations. No or very minor concerns about coherence. Thin data from 1 country. Serious concerns regarding adequacy and moderate concerns regarding relevance.
#17 Diet Diet was self-reported by donors as having potentially a negative and/or positive influence on the frequency of milk extraction and production. Frequency of milk extraction and milk production +/− Alencar and Seidl, 2010 [26] Quantitative Very low confidence ⊕○○○ One study with serious concerns about methodological limitations. No or very minor concerns about coherence. Thin data from 1 country. Serious concerns regarding adequacy and moderate concerns regarding relevance.
#18 Physical fatigue Fatigue was self-reported by donors as potentially having a negative influence on the frequency of milk extraction and production. Frequency of milk extraction and milk production Alencar and Seidl, 2010 [26] Quantitative Very low confidence ⊕○○○ One study with serious concerns about methodological limitations. No or very minor concerns about coherence. Thin data from 1 country. Serious concerns regarding adequacy and moderate concerns regarding relevance.
#19 Presence of negative emotions Some donors self-reported that the presence of negative emotions could negatively influence the frequency of milk extraction and production. Frequency of milk extraction and milk production Alencar and Seidl, 2010 [26] Quantitative Very low confidence ⊕○○○ One study with serious concerns about methodological limitations. No or very minor concerns about coherence. Thin data from 1 country. Serious concerns regarding adequacy and moderate concerns regarding relevance.
FACTORS RELATED TO DONOR’S FEATURES: Motivation to donate
#20 Availability of time Donors self-reported that the availability of time (to pump) could negatively or positively influence the frequency of milk extraction and production. Frequency of milk extraction and milk production +/− Alencar and Seidl, 2010 [26] Quantitative Very low confidence ⊕○○○ One study with serious concerns about methodological limitations. No or very minor concerns about coherence. Thin data from 1 country. Serious concerns regarding adequacy and moderate concerns regarding relevance.
FACTORS RELATED TO DONORS’ FEATURES: Breastfeeding and milk expression
#21 Experience of breastfeeding simultaneously Donors reported a decrease in donation frequency as their milk production decreased due to the process of breastfeeding itself (less excess than previously). Obstacle to remaining a donor: frequency of donation Machado et al., 2015 [29] Qualitative Low confidence ⊕⊕○○ One study with minor concerns about methodological limitations. No or very minor concerns about coherence. Thin data from 1 country. Serious concerns regarding adequacy and moderate concerns regarding relevance.
#22 Frequency of milk expression Some donors self-reported that the frequency of milk expression had a potentially positive influence on the frequency of milk extraction and milk production. Frequency of milk extraction and milk production + Alencar and Seidl, 2010 [26] Quantitative Very low confidence ⊕○○○ One study with serious concerns about methodological limitations. No or very minor concerns about coherence. Thin data from 1 country, serious concerns regarding adequacy, and moderate concerns regarding relevance.
#23 Nothing interferes with milk production Some donors self-reported that nothing interfered with milk production, which was seen as a positive influence on the frequency of milk extraction and production. Frequency of milk extraction and milk production + Alencar and Seidl, 2010 [26] Quantitative Very low confidence ⊕○○○ One study with serious concerns about methodological limitations. No or very minor concerns about coherence. Thin data from 1 country. Serious concerns regarding adequacy and moderate concerns regarding relevance.
#24 Time of day for expressing milk Donors self-reported that the time of day possibly influenced the frequency of milk extraction and production (increased production at night) Frequency of milk extraction and milk production + Alencar and Seidl, 2010 [26] Quantitative Very low confidence ⊕○○○ One study with serious concerns about methodological limitations. No or very minor concerns about coherence. Thin data from 1 country. Serious concerns regarding adequacy and moderate concerns regarding relevance.
FACTORS RELATED TO DONORS’ FEATURES: Other
#25 Mother’s routines (going out, contraceptive use, return to work) Some donors self-reported that going out, using contraception, or returning to work may have negatively influenced the frequency of milk extraction and production. Frequency of milk extraction and milk production Alencar and Seidl, 2010 [26] Quantitative Very low confidence ⊕○○○ One study with serious concerns about methodological limitations. No or very minor concerns about coherence. Thin data from 1 country. Serious concerns regarding adequacy and moderate concerns regarding relevance.
MILK BANK and HEALTH CARE–RELATED FACTORS: Support
#26 Milk bank support to donation The mother’s environment (support offered by MB staff) had a positive influence on her willingness to continue donating. Donor willingness to continue donating milk + Machado et al., 2015 [29] Qualitative Low confidence ⊕⊕○○ One study with minor concerns about methodological limitations. No or very minor concerns about coherence. Thin data from 1 country. Serious concerns regarding adequacy and moderate concerns regarding relevance.
#27 Family support to donation The support mothers received from their family positively influenced their willingness to continue donating. Donor willingness to continue donating milk + Machado et al., 2015 [29] Qualitative Low confidence ⊕⊕○○ One study with minor concerns about methodological limitations. No or very minor concerns about coherence. Thin data from 1 country. Serious concerns regarding adequacy and moderate concerns regarding relevance.
#28 Work impact and support Donors reported that incomprehension and lack of support at their workplace was an obstacle to remaining a donor. Obstacle to remaining a donor Machado et al., 2015 [29] Qualitative Low confidence ⊕⊕○○ One study with minor concerns about methodological limitations. No or very minor concerns about coherence. Thin data from 1 country. Serious concerns regarding adequacy and moderate concerns regarding relevance.
MILK BANK and HEALTH CARE–RELATED FACTORS: Logistics
#29 Distance from milk bank Donors reported that the distance they had to travel to deliver their milk to the milk bank (no home collection service being available) was an obstacle to becoming and remaining a milk donor. Obstacle to remaining a donor Machado et al., 2015 [29] Qualitative Low confidence ⊕⊕○○ One study with minor concerns about methodological limitations. No or very minor concerns about coherence. Thin data from 1 country. Serious concerns regarding adequacy and moderate concerns regarding relevance.
#30 Human resources Health care providers felt that a shortage of human resources in milk banks negatively affected the volume of the milk collected. Volume of milk donated Mondkar et al., 2018 [30] Qualitative Low confidence ⊕⊕○○ One study with minor concerns about methodological limitations. No or very minor concerns about coherence. Thin data from 1 country. Serious concerns regarding adequacy and moderate concerns regarding relevance.

* The confidence level scale ranges from: ⊕○○○ very low confidence; ⊕⊕○○ low confidence.