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. 2022 Dec 9;14(12):2753. doi: 10.3390/v14122753

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Expression of genes involved in activated protein C (APC) signaling in human peripheral blood mononuclear cells (PBMC) from patients with coronavirus disease 2019 (COVID-19) based on single-cell transcriptomics. (A). Matrix plot showing expression of genes related to APC signaling in patients with COVID-19 versus healthy individuals. (B). Dot plot representation of downregulated genes in patients with COVID-19. (C). Matrix plot showing expression of the main genes related to APC signaling according to cell types.