Table 2.
Dark toxicity and photodynamic activity of PzNPh and FePzNPh against A431, HaCaT, and SKOV-3.ip cells.
| Cell Line | Compound | * IC50 Dark (μM) | * IC50 Light (nM) | Photodynamic Index |
|---|---|---|---|---|
| A431 | PzNPh | 7.04 (6.13–8.16) |
190 (160–210) |
37 |
| FePzNPh | 24.18 (22.03–26.35) |
400 (370–440) |
60 | |
| HaCaT | PzNPh | 3.53 (2.22–5.10) |
40 (30–40) |
88 |
| FePzNPh | 18.33 (13.61–29.52) |
34 (20–40) |
539 | |
| SKOV-3.ip | PzNPh | 6.61 (3.088–15,84) |
180 (71–460) |
37 |
| FePzNPh | 9.6 (6.37–14.63) |
70 (60–80) |
137 |
* mean IC50 values and 95% confidence interval are indicated.