Table 2.
Characterization of the patches obtained in the study.
| Patch | (PGCL/PLGA) + CTX | (PGCL/PLGA) + DTX | (PLTMC/PLGA) + DTX | PLGCL + DTX | PLGA + DTX |
|---|---|---|---|---|---|
| Drug content [%] a | 5 | 3 | 3 | 3.7 | 3.3 |
| Average weight of the patch with 1 cm diameter [mg] | 20 | 17 | 18.5 | 11.6 | 6.3 |
| ΔH b | 23.2 | 28.7 | 5.8 | 5.1 | 4.5 |
| Tg [°C] c | −45.4/58.9 * | −42.4/60.9 * | 47.9 | 44.7 | 45.9 |
a on the basis of HPLC, b on the basis of DSC (I run), c on the basis of DSC (II run), * two values of Tg origins from separate glass transition temperatures detected on DSC curves for (PGCL/PLGA) + CTX and (PGCL/PLGA) + DTX.