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. 2022 Oct 5;23(11):e13507. doi: 10.1111/obr.13507

TABLE 2.

Current animal model evidence for HP food withdrawal

Animals express physical indicators of withdrawal during HP food withdrawal 22 , 23
Animals display affective indicators of withdrawal during HP food withdrawal 24 , 25
Animals show neural reward dysfunction during HP food withdrawal 22 , 23 , 24 , 25 , 26 , 27 , 28
Animals show increased CRF expression during HP food withdrawal 29
Animals show enhanced motivational drive/craving to consume HP food during HP food withdrawal 26 , 30 , 31
Animals show increased binge eating behavior during HP food withdrawal 28