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Schematic of the gNVU. (A) Artist’s rendering of the gNVU architecture; (B) positioning of the inlets and outlets are identified and the loading locations of the endothelial cells, astrocytes and pericytes are indicated; (C) the sites of introduction of the infection/therapeutic, control and sample collection sites are indicated. (D) Image of gNVU chips in a secondary container safe for use with select agents.
