The figure shows the different and most important fabrication techniques of PLGA, and the factors related to its degradation besides characteristics, responsiveness, advantages, and disadvantages. Due to the biodegradability and biocompatibility of PLGA polymer, it is widely used as a hydrophobic polymer to form various kinds of carriers such as polymersomes, emulsions, and polymeric micelles, and many more. Also, the figure shows some important PLGA characteristics, responsiveness, factors affecting its degradation, and some advantages and disadvantages of utilizing PLGA as a carrier system. The figure was created with BioRender.com.