Table 1.
Fold changes in mRNA levels of putative DNA-specific PRRs. Greater than 2 log2 regulation (*, p < 0.05; **, p < 0.01; ***, p < 0.001 with respect to the control group).
| PRR | Reference | pDNA | EP | pDNA + EP |
|---|---|---|---|---|
| Z-DNA binding protein 1 (Zbp1/Dai/Dlm) | [32] | 2.96 *** | 2.73 ** | 3.04 *** |
| Retinoic acid inducible gene I (RIG-I/Ddx58) | [33,34,35] | 1.97 *** | 0.87 | 2.05 *** |
| Interferon-activable protein 204 (Ifi204) | [36] | 3.13 *** | 3.55 *** | 3.92 *** |
| DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 (Ddx60) | [37] | 1.92 * | 1.31 | 2.01 ** |
| Cyclic guanosine monophosphate adenosine monophosphate synthase (Cgas) | [38] | 1.72 * | 1.58 * | 2.43 *** |
PRR, pattern recognition receptor, pDNA, plasmid DNA; EP, electroporation.