TABLE 3.
Associations between severity of sleep apnea during rapid eye movement (REM) sleep‐obstructive sleep apnea (OSA) and intima thickness
| Severity of REM‐OSA and intima thickness | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| REM‐AHI, events/h | N | Median (IQR) | Age‐adjusted | Adjusted Model 1 | Adjusted Model 2 | ||||||
| β‐coef. | (95% CI) | p | β‐coef. | (95% CI) | p | β‐coef. | (95% CI) | p | |||
| 0–4.9 | 222 | 0.08 (0.07–0.09) | Ref | Ref | Ref | ||||||
| 5–14.9 | 113 | 0.08 (0.08–0.09) | 0.034 | −0.002 to 0.069 | 0.062 | 0.032 | −0.004 to 0.068 | 0.085 | 0.041 | 0.004 to 0.078 | 0.029 |
| 15–29.9 | 99 | 0.08 (0.08–0.09) | 0.021 | −0.017 to 0.059 | 0.275 | 0.015 | −0.025 to 0.054 | 0.468 | 0.026 | −0.015 to 0.068 | 0.212 |
| ≥30 | 157 | 0.09 (0.08–0.10) | 0.058 | 0.025 to 0.092 | 0.001 | 0.043 | 0.006 to 0.080 | 0.021 | 0.055 | 0.017 to 0.092 | 0.005 |
AHI, apnea‐hypopnea index; CI, confidence interval; coef., coefficient; IQR, interquartile range; OSA, obstructive sleep apnea; REM, rapid eye movement.
Results from linear regression analysis with log‐transformed intima thickness as dependent variable. Model 1 adjusted for age, BMI, alcohol, smoking, and sex. Model 2 adjusted for age, body mass index, alcohol, smoking, sex, systolic blood pressure, low‐density lipoprotein, C‐reactive protein, and diabetes.