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. 2022 Dec 15;10(12):2156. doi: 10.3390/vaccines10122156

Figure 2.

Figure 2

Anti-OvHV-2 gB antibody responses in three animals immunized with OvHV-2 DNA plus AlHV-1-vectored vaccine [DNA+VV(IV)], AlHV-1-vectored vaccine only [VV(IV)], or mock control [Mock(IV)] and euthanized prior to challenge in experiment 1. Anti-OvHV-2 gB antibodies of both isotypes were detected by ELISA assays. (a) IgG kinetics in plasma. Green arrows represent immunizations and error bars are SEM; (b) IgG in bronchial alveolar lavage (BAL) fluid; (c) IgA in BAL fluid, and (d) neutralizing antibody response in BAL fluid. BAL fluid was collected at 46 days post-prime immunization. Bars in panels (b–d) indicate mean; ns, no statistically significant difference between groups; **, p < 0.01.