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Surface area of tissue abscess at indicated time points following challenge with S. aureus RN6390 and isogenic derivatives
| Strain | Inoculum (CFU) | Mean surface area ± SEM (mm2) of tissue abscess at:
|
||
|---|---|---|---|---|
| 24 h | 48 h | 72 h | ||
| RN6390 | 3.6 × 106 | 454.9 ± 62.2 | 399.6 ± 54.1 | 245.9 ± 35.9 |
| RN6911 | 2.6 × 106 | No visible lesion | No visible lesion | No visible lesion |
| SP6391 | 6.5 × 106 | 564.2 ± 53.0 | 536.9 ± 55.2 | 376.2 ± 35.7a |
Significant difference compared to RN6390 (P < 0.05).
